What is the standard treatment of BCC?
Surgical excision of BCC with a safety margin of surrounding healthy tissue
Mohs micrographic surgery: the tumor is removed layer by layer, and each layer is examined for tumor cells.
Why is Mohs method the best option?
Mohs surgery is the best method for ensuring both that the tumor is completely removed and that uninvolved skin is spared.
What are treatment alternatives of BCC?
Radiotherapy
Other options: cryosurgery, laser ablation, and topical chemotherapy with imiquimod or 5-Fluorouracil
When is radiotherapy indicated?
Patients who prefer radiotherapy over surgery (esp. elderly patients)
Large tumor or locations that are hard to reach
After incomplete surgical removal
What is the mechanism of action behind imiquimod?
Imiquimod is a successful treatment option in up to 80% of patients with small, superficial basal cell carcinoma. Imiquimod induces proinflammatory cytokines that stimulate an immune response against tumor cells
Indications: small, superficial tumors
What is the prognosis of BCC?
Excellent prognosis with surgical excision because of the low rate of metastasis
Last changed2 years ago