Role of the immune system
Innate immune cells
Antibodies
T-cells
Diversity of receptors in the immune system
Generation of new adaptive receptors
Principles of T cell activation
Clonal selection theory
Phases of an immune reaction
T cell development decreases with age
The efficacy of an immune response declines with age
Immunological memory decreases with age
With every infection the number of memory cells increases
Memory cell number increases, less new immune cells are produced
T cell repertoire is skewed in old individuals
Ageing of the immune system
Structural alterations during ageing
Immunosenescence
The function of immune cells is reduced
Inflammaging
Immune system & aging - overview
decline in T cell development
decline in efficacy of immune response
decreased immunological memory
structural alteration
impaired immune cell function
inflammaging
Last changed2 years ago
