How is HIV staged?
CDC categories of HIV are based on CD4 count in combination with current or previously diagnosed HIV-related conditions.
Any patient belonging in categories A3, B3 or C1-C3 is considered to have AIDS.
CDC classification (table).
Describe the WHO classification of HIV.
WHO classifies individuals with confirmed HIV infection according to clinical features and diagnostic findings:
Primary HIV infection: acute retroviral syndrome or asymptomatic
Clinical stage 1: persistent generalized lymphadenopathy (PGL) or asymptomatic
Clinical stage 2: e.g., unexplained moderate weight loss (< 10%), recurrent fungal/viral/bacterial infections
Clinical stage 3: e.g., unexplained severe weight loss (> 10%), unexplained chronic diarrhea (> 1 month), unexplained persistent fever (≥ 37.6°C intermittent or constant > 1 month), persistent/severe fungal/viral/bacterial infections , unexplained anemia (< 8 g/dL) and/or neutropenia (< 500 cells/mm3) and/or chronic thrombocytopenia (< 50,000/μL) for more than 1 month
Clinical stage 4: AIDS-defining conditions (e.g., Kaposi sarcoma, Pneumocystis pneumonia)
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