Name the main drug.
Montelukast
Name the medication class.
Leukotriene receptor antagonists (LTRAs)
The FDA has issued a warning because of reports of serious neuropsychiatric events with the use of montelukast.
Describe the mechanism of action.
Prevent leukotrienes from binding to their receptors (CysLT1)→ ↓ bronchoconstriction and inflammation
List indications.
Exercise-induced
Asthma aspirin-induced asthma
Long-term maintenance treatment (particularly in children)
List adverse effects.
Upper respiratory infection, pharyngitis
Headache, fever
Name a contraindication.
Hypersensitivity
Last changed2 years ago