To which antiemetic class does ondansetron belong to?
Serotonin receptor antagonists
Describe the mechanism of action.
Strong central antiemetic effect at the area postrema
Peripheral antiemetic effect via inhibition of the vagus nerve
Describe the clinical use.
Ondansetron is commonly used for generalized nausea.
Chemotherapy-induced vomiting, radiation-induced vomiting, and postoperative nausea and vomiting (PONV)