Name the category.
Antimigrene Agents
Name the main drug.
Topiramate
What kind of drug is it?
Second-generation anticonvulsant.
List indications.
Focal and generalized tonic-clonic epileptic seizures
Migraine prophylaxis
Idiopathic intracranial hypertension
Describe the mechanism of action.
Blockage of voltage-gated Na+ channels
↑ GABA
List adverse effects.
Glaucoma
Weight loss
Kidney stones
Cognitive dysfunction (e.g., decreased verbal fluency, cognitive speed, and working memory)
Sedation
Any contraindications?
NO
Any drug interactions?
Decreases efficacy of oral contraceptives
Last changed2 years ago