Name the category.
Antiparkinson Agents
Name the 2 main drugs.
Benzatropine
Procyclidine
What kind of drug class are they?
Anticholinergic drugs(muscarinic antagonists)
Describe the mechanism of action.
Inhibition of excitatory cholinergic neurons → ↓ concentration of acetylcholine
List indications.
Useful as monotherapy in patients < 65 years of age with tremor as the main symptom
Beneficial regarding tremor and rigidity but does not improve bradykinesia
When should they be avoided?
Usually avoided in patients > 65 years because they are more prone to anticholinergic side effects (e.g., urinary retention, delirium, constipation)
Side effects?
Last changed2 years ago
