Name the 2 main drugs.
Norepinephrine
EPINEPHRINE
Describe the action of epinephrine.
β > α (at high doses the α effect is predominant)
Stronger β2-receptor effect than norepinephrine
Describe the cardiovascular effects.
Raises BP (at high doses), HR, CO
List indications.
Anaphylaxis
Cardiac arrest
Septic shock
Postbypass hypotension
Asthma
Open-angle glaucoma
Describe the action of norepinephrine.
α1 > α2 > β1
Describe the effects of norepinephrine.
Raises BP (through vasoconstriction)
Lowers HR (reflex bradycardia) as a response to the increased mean arterial pressure (MAP), which counteracts chronotropic effects
No change or increase in CO
List indications for norepinephrine.
Neurogenic shock
Hypotension
Effects overview (table).
Adverse effects (table).
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