Describe the general clinical features.
PUD may be asymptomatic or manifest with a variety of clinical features, e.g., general dyspepsia or complications such as perforation or bleeding.
Describe the asymptomatic PUD.
Up to 70% of patients with peptic ulcers do not experience symptoms.
Patients who take NSAIDs are more likely to have asymptomatic ulcers and present with complications of PUD.
Describe the symptomatic PUD.
The most common symptom of PUD
Commonly located in the epigastrium
Often described as “gnawing” or “burning”
Can be related to meal intake depending on the location of the ulcer
Other associated symptoms
Nausea and/or vomiting