Gas transport and exchange in the blood stream
Common lung diseases
Chronic obstructive pulmonary disease
Cystic fibrosis
Interstitial lung disease
Acute respiratory distress syndrome
Mol 02 per mol HB
4
Methods for replacing lungs function
Non-invsaive ventilation
Mechanical ventilation
ECMO or ECCO2R
Transplantation
Bubble oxygenator
Rotation disc oxygenator
ECMO
Task: artificial lung (membrane oxygenator)
o2 enrichment
c02 removal
heat exchange
Short gas diffusion distance
High specific surface
Membrane contactor
ECCO2R
Extracorporeal carbon dioxide removal (ECCO2R) devices are specialized ECMOdevices that predominantly focus on CO2 removal.
In combination with mechanical ventilation: lower tidal volumes required
Driven by patient‘s cardiac output Pumpless
Problems with modern ECMOs
Dead zone formation
Encased autonomous zones
Bypassing and high fluid velocity on the walls due to packing voids
TPMS
Minimal surfaces which are periodic in three dimensions
Last changed2 years ago