How is the diagnosis typically made?
Diagnosis is based on clinical findings but is typically confirmed with early measurement of compartment pressures.
Describe the invasive compartment pressure measurement.
Indication: suspected ACS with equivocal clinical findings
Findings: The following support a diagnosis of ACS. 
Delta pressure ≤ 30 mm Hg (ΔP = diastolic blood pressure - intracompartmental pressure)
Rising or sustained elevation of compartment pressure
List additional studies.
Laboratory studies: to assess for rhabdomyolysis and crush syndrome and other potential complications
X-rays: to identify associated fractures
Ultrasound with and without Doppler: to rule out deep vein thrombosis and evaluate arterial blood flow