What is native chemical ligation? How does it work? What kind of bond results between the peptide fragments?
ligation method to ligate longer peptide chains
Chemoseletive reaction of the C-terminus and N-terminus of the Peptides
-> Issue : no side chain protection
use NCL
one cystein is introduced - high affinity of bonding
When would you recommend using recombinant synthesis and when SPPS (in combination with NCL)?
Last changed9 months ago
