Wie arbeiten cas12 und 9
Welche Faktoren haben einen Einfluss auf Knockin (KI) efficiency
Wie cas9 optimieren
Wie HDR optimieren
wie gRNA optimieren?
Wie bekommt man das HDR template in den Nukleus?
gRNA-HDR fusion
flanking the HDR template with truncated target sequences
exploring streptavidin-biotin interaction
Covalent tethering of the HDR template to Cas9
favoring HDR over NHEJ by RNAi or small molecules
Was ist CRISPR-READI?
selection of of transfected cells
selection nuclease active cells
Selection of KI events
exploring repair pathways other than HDR for targeted integration
KI by microhomolgy-mediated end joining
homology independent gene editing
EvolvR
CRISPR-associated transposases / recombinases
base editors
Was ist die Lösung zu folgendem Problem?
Prime editors
Gene editing therapy
TIGR-Tas
Last changed21 days ago
