Describe the diagnostic confirmation of COVID-19.
Diagnostic confirmation is based on viral testing for COVID-19.
Test all individuals with symptoms of and/or exposure to COVID-19 for current infection
Collect specimens from the upper respiratory tract (e.g., nasopharyngeal, oropharyngeal).
Obtain a viral test (e.g., nucleic acid amplification test) or antigen test to diagnose current infection.
When should imaging be used for screening?
Should not be used as a screening modality or the sole diagnostic modality for COVID-19
May be indicated to assess disease severity and rule out alternative diagnoses
Describe the collection of specimens.
For all individuals: Obtain an upper respiratory tract specimen.
Preferred method: nasopharyngeal specimen (NP specimen)
Alternative methods
Oropharyngeal (OP) swab (i.e., throat swab)
Nasal midturbinate (NMT) swab
Anterior nares specimen
Saliva specimen
Nasopharyngeal wash/aspirate or nasal aspirate
If using both NP and OP swabs: Combine in a single tube.
For mechanically ventilated individuals with a negative upper respiratory tract specimen: Obtain a lower respiratory tract aspirate or bronchoalveolar lavage.
List DDs.
Common cold
Influenza
Allergic rhinitis
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