Name a main “drug”.
Calcium salts
List uses.
Dietary requirements
Hypocalcemia
Hypocalcemic tetany
Hypoparathyroidism
Latent tetany
Osteoporosis
Glucocorticoid-induced osteoporosis
Anticonvulsant-induced hypocalcemia
Osteomalacia
Rickets
Hyperphosphatemia in chronic renal failure
etc. etc. etc.
List contraindications.
Ventricular fibrillation.
Hypercalcemia.
Hypophosphatemia.
Renal calculi.
IV administration contraindicated when serum calcium concentrations are above normal.
List common adverse effects.
Constipation, nausea, vein irritation.
With which antibiotics should calcium not be given?
Calcium complexes tetracycline antibiotics rendering them inactive
Describe the actions.
Calcium is essential for maintenance of the functional integrity of nervous, muscular, and skeletal systems and cell-membrane and capillary permeability.
Calcium is an important activator in many enzymatic reactions and essential to a number of physiologic processes including transmission of nerve impulses; contraction of cardiac, smooth, and skeletal muscles; renal function; respiration; and blood coagulation.
Calcium plays regulatory roles in the release and storage of neurotransmitters and hormones, in the uptake and binding of amino acids, and in cyanocobalamin (vitamin B12) absorption and gastrin secretion.
Calcium accounts for 1–2% of adult body weight, and more than 99% of total body calcium is found in bone and teeth. [ref]
Calcium is present in blood, extracellular fluid, muscle, and other tissues where it has roles in mediating vascular contraction and vasodilation, muscle contraction, nerve transmission, and glandular secretion.
Skeleton serves as a reservoir for calcium in addition to serving as a structural support for the body.
Conditions associated with reduced concentrations of circulating estrogen alter calcium homeostasis.
Reduced estrogen concentrations are associated with reduced calcium absorption efficiency and increased bone turnover rates.
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