Name the cetegory.
Anticonvulsants
Name the main drug.
Ethosuximide
What is the indication for ethosuximide?
First-line for absence seizures
Ethosuximide is preferred over valproate for school-age children because it has fewer side effects.
Describe the mechanism of action.
Inhibition of voltage-gated calcium channels (T-type) in neurons of the thalamus
Describe adverse effects of ethosuximide.
Gastrointestinal symptoms
Allergic skin reactions (urticaria, Stevens-Johnson syndrome)
Pancytopenia
Fatigue
Headache
Myopia
To remember that the most important side effects of ethoSUXimide are Steven-Johnson syndrome, fatigue, headache, ABdominal upset, and ALLErGies (e.g., urticaria), think of “It sucks that Steven's FATher has given everyone a headache with his ABsurd ALLEGorizations.”
List contraindications.
Pregnancy (especially valproate and carbamazepine)
Name one important drug interaction.
Increases serum levels of phenytoin
Zuletzt geändertvor 2 Jahren