Name the category.
Immunomodulators
Name the 2 main drugs.
EPINEPHRINE
Hydrocortisone
What kind of drug is epinephrine?
Sympathomimetic
Describe the action of epinephrine.
β > α (at high doses the α effect is predominant)
Stronger β2-receptor effect than norepinephrine
Describe the cardiovascular effects of epinephrine.
Raises BP (at high doses), HR, CO
List indications for epinephrine.
Anaphylaxis
Cardiac arrest
Septic shock
Postbypass hypotension
Asthma
Open-angle glaucoma
Side effects table.
What kind of potency does hydrocortisone have?
Hydrocortisone is the synthetic equivalent of endogenous cortisol and its glucocorticoid and mineralocorticoid potency is considered to be “1”
How long is hydrocortisone acting?
Short acting (8-12 hours)
List common routes of administration.
Oral
Injectable
Topical
How are the hydrocortisone activities?
Glucocorticoids with some mineralocorticoid activity
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