List gastrointestinal symptoms.
Chronic or recurring diarrhea: steatorrhea
Flatulence, abdominal bloating, and pain
Nausea/vomiting
Lack of appetite
Constipation (rarely)
List extraintestinal symptoms and associations.
Malabsorption symptoms: fatigue, weight loss, vitamin deficiency, iron deficiency anemia, osteoporosis, hypocalcemia
In children: failure to thrive, growth failure, delayed puberty
Dermatologic associations: dermatitis herpetiformis
Neuropsychiatric symptoms: peripheral neuropathies (numbness, burning and tingling of the hands and feet) , headache, ataxia, depression, irritability [4]
Gynecological associations: reduced fertility or infertility
Endocrine associations: autoimmune thyroid disease, type 1 diabetes mellitus
Associated chromosomal syndromes: Turner syndrome, Down syndrome
Other associated conditions: autoimmune hepatitis, irritable bowel syndrome, inflammatory bowel disease, rheumatoid arthritis, sarcoidosis, selective IgA deficiency
In both children and adults, mild or asymptomatic cases are more common than the classic presentation of the disease.
Zuletzt geändertvor 2 Jahren