Describe the onset of manifestation.
Testicular dysgenesis and subsequent testosterone deficiency manifest at the onset of puberty (symptoms are rare during childhood).
List signs and symptoms of hypoandrogenism.
Eunuchoid growth pattern: tall, slim stature with long extremities (Growth plate closure is delayed )
Gynecomastia
Reduced facial and body hair
Testicular atrophy [9]
Reduced fertility and libido
Frequent azoospermia
Micropenis
Osteoporosis (common feature in adulthood)
Describe signs of possible developmental delay.
Neurocognitive dysfunction (impaired executive function and memory, decreased intelligence)
Language impairment (affects expression more than comprehension)
Poor social skills
List associated disorders.
Mitral valve prolapse
Increased risk of breast and testicular cancer
Metabolic syndrome
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