If the observed proportion of differences (D) between two protein sequences is 0.42, the expected proportion of differences (K) is:
The mutation responsible sickle cell anemia (and malaria resistence) occurs
in:
If all nucleotides are used with equal frequency, the maximum divergence we expect between two DNA sequences is:
The homeodomain is a protein domain of __ amino acids.
If all amino acids are used with equal frequency, we expect two random protein sequences to be _____ identical:
Which type of site is expected to show the least divergence between species?
Which of the following DNA sequence changes is a transition?
Which of the following represents a typical value of the transition/transversion ratio for DNA substitutions?
The ratio dN/dS is also sometimes referred to as:
Which of the following is expected for a pseudogene?
According to the molecular clock, sequence divergence between species depends on:
The most parsimonious tree is the one that
Which one of the following statements about the great apes is correct?
Which of the following represents a rare genetic change (RGC)?
Which of the following statements about mammalian mitochondrial DNA is true?
Mexican and South American dog breeds:
According to the neutral theory of molecular evolution, both divergence between species and polymorphism within species depend on:
A negative value of Tajima’s D is expected when there is:
What is the major difference between the HKA (Hudson-Kreitman-Aguade) and the MK (McDonald Kreitman) tests?
Which of the following statements is true of background selection?
According to the fossil record, which was the first hominin to leave Africa?
Which of the following statements about Mitochondrial Eve is true?
A mutation in the CCR5 gene is associated with:
What type of genetic variation is associated with number of children in the Icelandic population?
Clone-by-clone genome sequencing is also known as ________ genome sequencing?
What type of species has the largest known genome?
Which of the following methods are used for gene expression profiling?
The defining feature of a cis-regulatory variant is that it:
Which pair of species/taxa are male-heterogametic?
In the male germline of Drosophila melanogaster:
Which of the following requires an “outgroup” sequence?
Which of the following requires a protein-coding sequence?
Which of the following would suggest positive selection?
A positive value of Tajima’s D suggests an excess of:
What type of variation in the Amylase gene is associated with starch digestion in humans?
A deletion in which gene is associated with HIV/AIDS resistance in humans?
The mutations responsible for lactase persistence in European and African pastoralist populations occurred:
Which of the following can explain the observed positive correlation between DNA polymorphism and recombination rate?
Which model of human evolution involves extensive gene flow among populations?
Who is known for the hypothesis “ontogeny recapitulates phylogeny”?
The vertebrate homolog of the Drosophila eyeless gene is known as:
The key genes that control flower development in plants are:
Which method can be used for PTGS (post-transcriptional gene silencing)?
Which of the following cannot be performed using only within-species polymorphism data?
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