Membranes in Biotech
Flow sheet of a biotechnological process
Upstream Processing:
Downstream Processing:
Membrane separation mechanisms
What are advantages of membrane (bio)-reactors?
increasing conversion and selectivity,
synergetic effects,
removal of toxic byproducts,
less process steps
Which is the first step in a bioprocess?
biomass/organisms are grown in bioreactors
Why membrane (bio)-reactors?
Flow sheet of a downstream process
Microfiltration - Sterile filtration
Virus filtration
Increase of packing density
Ultrafiltration — Tangential flow filtration
Ultrafiltration – Process configurations
Diafiltration
Chromatography in general
Membrane Chromatography – Separation mechanisms
Advantages of membrane chromatography vs. packed bed columns:
Applications of chromatography in general
Membrane chromatography
Take home message
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