How do we hear?
What is the threshold for deafness and disabling hearing impairment?
Deafness:
81 dB or greater hearing threshold (“4FAHL”: avg at 0.5, 1, 2, 4 kHz)
Disabling hearing impairment
35 dB or greater hearing threshold (avg at 0.5, 1, 2, 4 kHz) in better ear
Effects and burden of hearing impairment
Impaired development of speech, language, cognitive skills in children
Slow progress in school
Difficulties in obtaining, performing and keeping an occupation
Social isolation and stigmatization in all ages and both sexes
Profound social and economic effects in communities and countries.
What gadget can be use for electrical stimulation of the auditory nerves?
At first: only one wire (single channel), not possible to understand speech, but ok with lip reading
How does a choclea implant work?
With an implant, instead, the devices pick up sound and digitize it, convert that digitized sound into electrical signals, and transmit those signals to electrodes embedded in the cochlea. The electrodes electrically stimulate the cochlear nerve, causing it to send signals to the brain.
What are the parts of a cochlea implant?
External:
one or more microphones that pick up sound from the environment
a speech processor which selectively filters sound to prioritize audible speech
a transmitter that sends power and the processed sound signals across the skin to the internal device by radio frequency transmission
Internal:
a receiver/stimulator, which receives signals from the speech processor and converts them into electric impulses
an electrode array embedded in the cochlea
House/3M single-channel cochlear implant
amplifier = Verstärker
What are the single-channel limitations?
Temporal coding in nerve fibers limited to <1 kHz
What are the approaches for Multi-Channel cochlear implants?
Feature-Extraction Strategies
Waveform Strategies
compressed analog
Continuous Interleaved Sampling (CIS)
Advanced Combinational Encoder (ACE)
Waveform strategies: Continuous Interleaved Sampling. What are the steps of improving/translating the sound?
sound signal is amplified -> filtered -> envelope=fluctuation -> compression -> electrode transmits
one electrode at a time
What are vocoder?
Simulate information reduction in CIs
vocoder can be used to reduce the complexity of audio information -> signal processing
In general, a rich input signal is replaced by a sparse output signal
vocoders have become synonymous with cochlear implant (CI)
Simulate information reduction in CIs for normal-hearing listeners
Shows information that is transmitted by a cochlear
What are the Signal Processing Strategies of a cochlea?
Compressed Analog
Advanced Combination Encoder (ACE)
Feature Extraction (F0/F1/F2 strategies)
What are the defferent ways of stimulation of the cochlear?
Stimulation Modes:
Monopolar: wide current spread, low threshold (clinically common).
Bipolar/Tripolar: more focused stimulation, but higher thresholds.
Put up an electric field -> cell membrane gets charged (channels open for ions)
pulse usually is followed by an action potential
3: not beeing used, too quiet
Electrical stimulation of the auditory system. How do the curves of the electric pulses look like? What are the pulse types?
Pulse Types:
Biphasic pulses: preferred for charge balance.
Vary amplitude, phase duration, and inter-phase gap (IPG).
Pulse = Stimulus
What is a simple model for the electrically stimulated auditory nerve?
The leaky integrate-and-fire model:
Simulates auditory nerve response.
Includes spike threshold, noise, and refractory period.
Captures firing probability, rate adaptation, and latency.
bucket gets filled and bucket has holes
🔸 Rate Adaptation:
High stimulation rates → adaptation, decreased neural response.
Limits how fast pulse trains can carry useful information.
(a) Sketch into the axes below the behavior of the firing probability of a single auditory nerve fiber as a function of stimulation current for monophasic (or biphasic) electrical pulses in cochlear implants. Label the axes!
(b) Label the firing threshold in your graph. [1 P]
(c) Briefly describe what are the T- and C-level in clinical cochlear implants.
What is the reaktion of nerves on pulses? What happens when you stimulate at high rates?
action potential
with rate adaptation (if there are too many pulses, AP can not keep up - nerve would eventually stop firing)
What happens if you change the pulses per second? How do patients respond?
Numbers=elektrodes are ranked by pitch by patient
rankings are off because nerver fibers have died, so multiple electrodes stimulate the same instead of different
goal: patients can distinguish the electrodes
What is a limitation for the frequency resolution? What is a solution?
Limitation: current spread and # of electrodes
Solution: Use current steering: gain a few “extra pitches” in-between electrodes by steering “center of gravity” of current from one electrode to another
How can we transmit Speech modulation ranges to the nerve ranges?
compression
Comfortable level (C-level)
Threshold (T-level)
New development: Stimulation by one electrode and record nerve activity by another activity
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