What should be the initial test to confirm and classify anemia?
CBC with differential
What is the most important parameter in the diagnostic workup of anemia?
RBC indices —> Mean corpuscular volume (MCV)
—> Based on MCV, further testing should be performed to determine the underlying caus
Why is the platelet count, WBC count and WBC differential important?
Abnormalities in platelet count, WBC count, and WBC differential may provide signs of the underlying diagnosis.
Abnormal leukocytes may suggest bone marrow failure or bone marrow malignancy (e.g., aplastic anemia, leukemia, myelodysplastic).
Pancytopenia can result from several etiologies (e.g., peripheral cell destruction or sequestration in hypersplenism, aplastic anemia, infection).
Last changed2 years ago