Describe the use of a bone marrow biopsy.
Rarely used in the workup of anemia
Indications include pancytopenia and/or abnormal cells on the CBC or peripheral blood smear (e.g., blasts)
Prussian blue staining if sideroblastic anemia is suspected
For which pathologies can a bone marrow biopsy be used ?
Aplastic anemia
Myelodysplastic syndromes
Myeloproliferative neoplasm
Malignant invasion of the bone marrow
Which imaging studies can be obtained for anemia?
not routinely indicated for the workup of anemia unless bleeding is suspected
Consider endoscopy and/or colonoscopy in patients with anemia and positive FOBT.
Consider abdominal ultrasound to evaluate for hypersplenism, liver disease, or renal disease.
Consider CT and/or PET scan if malignancy is suspected.
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