Describe the initial therapy.
Treatment is based on the stage of heart failure.
Additional therapies are added to the baseline medications as symptoms worsen.
From stage B onward, device therapy can be considered alongside medical therapy.
Start all new medications at the lowest recommended dose and slowly titrate up to the target dose where applicable.
The following table deals predominantly with the management of HFrEF; there is a paucity of evidence supporting best practice in HFpEF.
Which drugs should be given in patients of stage B HF?
ACE inhibitors or Angiotensin receptor blockers
Beta blockers
Stage B overview.
Stage C patients receive additional drugs. Which?
Aldosterone antagonists
Loop/ Thiazide diuretics
Isosorbide dinitrate/hydralazine
Angiotensin receptor-neprylisin inhibitors
SGLT2 inhibitors
Stage C drugs.
Which drugs improve prognosis?
Drugs that improve prognosis are beta blockers, ACE inhibitors, ARNIs, aldosterone antagonists, hydralazine with nitrate, and SGLT2 inhibitors.
What is the value of diuretics and digoxin?
Diuretics and digoxin improve symptoms and significantly reduce the number of hospitalizations.
Drugs used in HF (picture).
Which drugs can be given in refractory symptoms?
Last changed2 years ago
