List causes for hepatotoxicity.
Long-standing alcohol use disorder (one of the two most common causes of chronic liver disease in the US)
Medications (e.g., acetaminophen, amiodarone, chemotherapy drugs such as methotrexate)
Ingestion of aflatoxin (produced by Aspergillus) [3]
Industrial chemicals such as tetrachloromethane and various pesticides
List causes for inflammation (hepatitis).
Chronic viral hepatitis: hepatitis B, hepatitis D, and hepatitis C (most common cause of cirrhosis in the United States)
Primary biliary cholangitis
Primary sclerosing cholangitis
Autoimmune hepatitis
Parasitic infections (e.g., schistosomiasis, leishmaniasis, malaria)
IgG4 cholangiopathy
List causes for metabolic disorders.
Nonalcoholic steatohepatitis (NASH)
Hemochromatosis
Wilson disease
α1-antitrypsin deficiency
Porphyrias
Glycogen storage disease
Cystic fibrosis
Hereditary fructose intolerance
Describe causes for hepatic vein congestion or vascular anomalies.
Budd-Chiari syndrome
Cardiac cirrhosis (congestive hepatopathy)
Osler-Weber-Rendu syndrome
What is the cryptogenic cirrhosis?
cirrhosis of uncertain etiology despite adequate diagnostical efforts
Last changed2 years ago